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Clue: Pained reaction
Pained reaction is a crossword puzzle clue that we have found once. There are related clues (shown below).
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New York Times - September 11, 2005
Related Clues
Look that may accompany a groan
Pain result
Pained reaction
React to a bad joke, perhaps
React to a really bad pun
Reaction to a friend's mistake
Recoil in pain
Response to a gotcha
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